Examine together with your well being treatment professional if any of the next Uncomfortable side effects carry on or are bothersome or Should you have any questions about them:

Anaesthetics: concomitant administration of codeine and anaesthetics may lead to enhanced CNS despair and/or respiratory despair and/or hypotension.

Administration for the duration of labour may perhaps depress respiration inside the neonate and an antidote for the kid need to be available.

Musculoskeletal and connective tissue Diseases: Uncontrolled muscle mass actions. Muscle rigidity may well take place following higher doses.

Further assistance and checking could possibly be essential when prescribing for individuals vulnerable to opioid misuse.

No satisfactory reports are performed in animals to determine irrespective of whether acetaminophen and codeine have a possible for carcinogenesis or mutagenesis. No ample scientific studies are already performed in animals to ascertain whether or not acetaminophen has a possible for impairment of fertility.

Vigorous supportive therapy is needed in severe intoxication. Techniques to Restrict the continuing absorption of the drug needs to be commonly executed since the hepatic injuries is dose dependent and happens early in the midst of intoxication.

There have already been reviews in the released more info literature that codeine supplied publish-operatively in children immediately after tonsillectomy and/or adenoidectomy for obstructive sleep apnoea, triggered unusual, but daily life-threatening adverse occasions which include Loss of life (see also part 4.

Breast feeding Administration to nursing Gals is just not advisable as codeine might be secreted in breast milk and will induce respiratory melancholy within the toddler.

Talk to your health practitioner or pharmacist if You're not absolutely sure whether it is Protected that you should push although having this drugs.

Drug withdrawal syndrome Prior to starting procedure with any opioids, a discussion really should be held with people To place in position a withdrawal strategy for ending treatment method with Codeine Phosphate.

Overuse or misuse may perhaps end in overdose and/or Loss of life. It is important that people only use medicines that are prescribed for them for the dose they have already been prescribed and don't give this medication to any individual else.

Serum acetaminophen concentrations really should be acquired right away When the affected individual provides four hours or maybe more soon after ingestion to evaluate probable threat of hepatotoxicity; acetaminophen levels drawn a lot less than 4 hrs write-up-ingestion could possibly click here be misleading. To obtain the absolute best outcome, NAC must be administered without delay where by impending or evolving liver injuries is suspected. Intravenous NAC may be administered when circumstances preclude oral administration.

Making use of this medication with any of the following is generally not suggested, but could be unavoidable in some cases. If made use of jointly, your health care provider may well change the dose or how frequently you use this medication, or Provide you with special Recommendations about using foodstuff, Alcoholic beverages, or tobacco.